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Evidence-based oncology

The Institute is involved in the preparation of systematic reviews and clinical guidelines in the field of oncology in accordance with the AWMF regulations and the internationally recognized Cochrane methodology. This includes the creation of evidence profiles, the application of the GRADE approach, and the application of the evidence-to-decision framework.

Working group

  • Nora Cryns
  • Mario Czenar
  • Moritz Ernst
  • Marius Goldkuhle
  • Caroline Hirsch
  • Claire Iannizzi
  • Nina Kreuzberger
  • Ana-Mihaela Zorger

Ongoing projects

S3 Guidelines - Coordination

  • Hodgkin's lymphoma (German Cancer Aid (DKH))
  • Chronic lymphocytic leukemia (DKH)
  • Diffuse large B-cell lymphoma (DKH)
S3 guidelines - Methodological Support, Preparation of Evidence

  • CPAP for obstructive sleep apnea (European Respiratory Society (ERS))
  • Thyroid carcinoma (DKH)
  • Vulvar cancer (DKH)
  • Oncological exercise therapy (DKH)
  • Breast cancer/breast reconstruction (DKH)
Systematic Reviews

  • Vaccinations in cancer patients: A Cochrane systematic review with meta-analyses (VACCAP; BMBF funding code 01KG2104)
  • Interventions for the treatment of fatigue in adult cancer patients: a Cochrane systematic review with meta-analysis (FATI, BMBF funding code: 01KG2017)
  • Positron emission tomography-adapted therapy for first-line treatment in adults with Hodgkin lymphoma
  • Chemotherapy alone versus chemotherapy plus radiotherapy for adults with early stage Hodgkin lymphoma
  • Antifungal prophylaxis with azoles to prevent invasive fungal infections in adult patients with haematological malignancies and neutropenia
Further Projects

  • Patient reported outcomes (European Hematology Association (EHA))
  • Cardiotoxicity of oncological preparations (European Hematology Association)

Completed projects

Systematic reviews

  • Bone active agents for the prevention of bone loss in women with early or locally advanced breast cancer: a systematic review and network meta-analysis (BMBF funding code: 01KG1806)